peptides
MOTS-c 40mg
Extended-supply MOTS-c vial for longer research arcs.
Research-observed benefits
- ›Mitochondrial function
- ›Endurance capacity
- ›Insulin sensitivity
- ›Metabolic homeostasis
Findings reported in in-vitro / preclinical research literature. Not therapeutic claims.
Reconstitution helper
Suggested: 3 mL BAC water → 13.33 mg/mL
CAS Number
—
Purity
99%+
Molecular Formula
—
Stock
200 units
Order type
Purchase option
Quantity
Total
$70
For in-vitro research only. Not for human consumption, diagnostic, or therapeutic use. Storage at -20°C recommended for lyophilized peptides.
MOTS-c 40mg — Full Research Breakdown
Tailored information for researchers. All content is for in-vitro / preclinical research context only — not medical advice.
Mechanism of Action
16-amino-acid mitochondrial-derived peptide encoded in the mitochondrial 12S rRNA gene. Activates AMPK, enhances glucose uptake, and increases mitochondrial biogenesis.
How It Helps
Improves cellular energy output, insulin sensitivity, and endurance capacity — particularly compelling in aging and metabolic-stress research models.
Half-Life
~2.5 hours plasma; cellular effects sustained 24–48 hours
Onset of Effects
Subjective energy shifts within 1–2 weeks of consistent dosing.
Administration
Subcutaneous injection.
Storage
Lyophilized: –20°C, stable 24 months. Reconstituted: refrigerated, 30 days.
Reconstitution Guide
10 mg + 2 mL BAC → 5 mg/mL (0.5 mg per 0.1 mL). 40 mg + 3 mL → 13.3 mg/mL.
Precise Dosing Protocols
Standard research dose
- Dose:
- 5–10 mg/week
- Frequency:
- 1–2× weekly SC
- Duration:
- 8–12 week cycles
Endurance/metabolic focus
- Dose:
- 10 mg split into 2 doses
- Frequency:
- Twice weekly
- Duration:
- 12 weeks
Stacks Well With
- ›NAD+ (mitochondrial coenzyme synergy)
- ›Retatrutide (metabolic stack)
- ›Tesamorelin (body comp)
Research-Observed Side Effects
- •Mild injection-site reaction
- •Occasional transient flushing
Translational Cautions
- •Limited human translational data — exercise standard research caution
Cycling Guidance
12-week on / 4-week off cycles are common to assess durability of AMPK activation.
Research Highlights
- ▸Lee et al. 2015: AMPK-mediated improvement in insulin sensitivity in murine models.
- ▸Reverses diet-induced obesity phenotypes in published preclinical data.
- ▸Levels decline with age — proposed longevity biomarker.